… tested the effect and the efficacy of ACE inhibitors (captopril, enalapril, … Nevertheless, digoxin
is the most common drug used to … of cardiovascular and renal diseases, but its long-term …

… Effects of long-term monotherapy with enalapril, metoprolol, and digoxin on the progression
of left ventricular dysfunction and dilatation in dogs with reduced ejection fraction. Circulation…

… with HF and reduced left ventricular (LV) ejection fraction. This … with moderate CRS, long-term
monotherapy with Sac/Val … , namely CRS dogs treated with either an ACE inhibitor alone or …

… it less desirable than ACE inhibitors for long-term use. GI upset … , digoxin, and enalapril for
suspected left ventricular dilation. … dog model of ischemic DCM, three months of metoprolol …

… failure and preserved left ventricular ejection fraction (HFpEF). … , it appears that the left ventricle
does not dilate much and LVEF … that long-term monotherapy with elamipretide in a canine …

… Effects of long-term monotherapy with enalapril, metoprolol, and digoxin on the progression
of left ventricular dysfunction and dilation in dogs with reduced ejection fraction. Circulation …

… developed defined as left ventricular ejection fraction (LVEF) < … for evaluating dilated
cardiomyopathy in canine model (23). … heart failure with reduced ejection fraction in the canine …

… BTHS, typically appearing as dilated cardiomyopathy (DCM) … Furthermore, in the canine HF
model, long-term elamipretide … In dogs with HF with reduced ejection fraction (HFrEF), three …

… and dogs after acute MI [28,31], and in patients with reduced left … eight-week phase to follow
the long-term effects on HF. … of firibastat or enalapril on left ventricular ejection fraction (LVEF…

… in which the ventricular wall becomes dilated. On the other hand… including propranolol,
atenolol, metoprolol, acebutolol, and … adults with heart failure with preserved ejection fraction. …